The NFL released its full 272-game schedule Wednesday. Here's a look at the most interesting matchup in each of the 18 weeks.

The leaks are over, the 2025 NFL schedule has been released! Now that we have the full 272-game regular-season schedule, here are a few highlights: Eagles will host the Cowboys in

For starters, they won't be suffering from much jetlag in 2025—Cincinnati travels a combined 8,753 miles in 2025, the least in the league. A chunk of that travel comes early in the season, with four of their first six games away from home.

Everything you need to know about the 2025 NFL Schedule release including date and time2025 NFL Schedule Release: Updates, leaks, season opener set

While the Seahawks were all about that action and the Chargers met the high bar they have set, the Colts had apparent second thoughts.

Another important benchmark of the NFL offseason is here as the league announced the full 2025 schedules for all 32 teams.

The NFL officially released its full slate of games for the 2025 season on Wednesday. The schedule is full of intrigue as the Bills look to build toward their sixth-consecutive AFC East crown. However, Buffalo will face off against multiple teams that have ended their season in recent years.

At bet365, the Giants are tied with the Browns for the best odds to finish with the worst record in the league. They have more faith in a New Orleans Saints team that will start any of Spencer Rattler, Tyler Shough or Jake Haener at quarterback this season. That speaks volumes about the perception of the Giants.

In a statement to Pro Football Talk, the Colts explained that they deleted their schedule release video due to a Microsoft licensing issue, and what they described as an "insensitive" joke directed at Miami Dolphins wide receiver Tyreek Hill, who they face in Week 1 of the upcoming season.