Nathan Michael Quinn, 45, of Port Charlotte died after losing control of a F-150 pickup truck along I-4 in Lakeland, near ...

Wilmer Bonilla, a man from Orange County, was arrested early Monday morning for street racing on Interstate 4. Deputies ...

Channel 9 is investigating a video showing a group of e-bike riders slowing traffic on Interstate 4 in downtown Orlando.

A Daytona Beach man died in a motorcycle crash on an I-4 ramp in Orange County. The incident occurred on Tuesday night, and ...

Interstate 4 in Osceola County near ChampionsGate reopened Monday evening following a crash involving a truck hauling fertilizer that shut down both the westbound and eastbound lanes all afternoon.

Routed for Hours as Investigation was Underway LAKELAND, Fla. - Interstate 4 eastbound was completely shut down for several hours Tuesday morning following a fatal crash near Exit 28 (Memorial ...

OSCEOLA COUNTY, Fla. – A semitruck became engulfed in flames Monday morning after a crash with a car on Interstate 4 in Osceola County, shutting down the interstate for hours.

One person was dead and at least one car fully engulfed in flames by the time responders arrived shortly before 2 a.m. Monday to the crash on Interstate 4 near Conroy Road.

A vehicle struck and killed a black bear on Interstate 4 near Lake Mary, with the FWC notified to remove the animal.

ALTAMONTE SPRINGS, Fla. (WFLA) — An Interstate 4 driver who was clocked at driving 155 mph on the Florida highway was arrested early Sunday, the Florida Highway Patrol said.

SEMINOLE COUNTY, Fla. — An infamous landmark along Interstate 4 may get its first tenant since construction began over 24 years ago. The owner of the Majesty Building, referred to by some as ...