Cade Klubnik and the Clemson Tigers will host Garrett Nussmeier and LSU in the 2025 college football season opener. Here's when they'll kick off.

Clemson football is set to open its 2025 campaign against LSU in a primetime slot, giving them the stage to prove their dominance right away.

Coach Dabo Swinney’s Tigers went 10-4 last season and returned to the College Football Playoff for the first time since 2020. Clemson returns star quarterback Cade Klubnik (43 total touchdowns) and 15 other starters on offense and defense and ranks No. 1 in the country in total returning production, per ESPN.