Heavy snow and ice will fall in eight states from Texas to the Carolinas late Monday into Wednesday, leading to dangerous conditions in places where the severity of snowfall could be historic.

Snow and ice had been forecast to fall across the I-10 corridor into Lake City and Jacksonville, with perhaps a few ice pellets as far south as Ocala. All precipitation was set to end by daybreak.

The Alzheimer’s disease (AD) “epidemic” affects the entire country, but states like Alabama, Georgia, Louisiana, Mississippi, and South Carolina are particularly hard-hit. People born in this region, ...