Its flagship academic medical centers in Boston, Massachusetts General Hospital and Brigham and Women’s Hospital, anchor a health care hub that is arguably the best in the country, if not the world. Reimbursement rates from insurers are growing more slowly than expenses.

BOSTON - Mass General Brigham, the largest health care system in Massachusetts, announced layoffs Monday that will affect hundreds of workers, citing a $250 million projected budget gap.

Wentworth-Douglass Hospital was not spared from layoffs by Mass General Brigham as it cited an anticipated "budget gap" of $250 million.

Mass General Brigham attributed the layoffs to an expected budget shortfall of $250 billion over the next two years.

Mass General Brigham plans to lay off hundreds of employees over the next two months as part of a broader restructuring effort to address a significant budget deficit. In a statement released Monday,

Facing rising costs and hoping to make its sprawling network more efficient, the state’s largest private employer aims to cut payroll costs by over $200 million.

Mass General Brigham announced layoffs for hundreds of administrative and management employees on Monday in anticipation of a $250 million budget gap, an unprecedented decision for Massachusetts’ largest private employer.

At least three high-level employees at Nantucket Cottage Hospital left abruptly recently, after the parent company of the island's only hospital announced layoffs last week.

Mass General Brigham announced mass layoffs aimed to bridge a $250 million budget gap projected over the next two years in a letter to employees Monday — meaning potentially hundreds of

The largest private employer in Massachusetts is planning significant layoffs citing a significant budget deficit.