A shorter course of prophylactic antibiotics, or even no course at all, appeared to be noninferior to longer courses in ...

Pooled data show that no or shorter antibiotic prophylaxis for upper GI bleeding in cirrhosis is very likely noninferior to longer courses for all-cause mortality, challenging long-standing advice.

Current guidelines for patients with cirrhosis and upper-GI bleeding recommend 5 to 7 days of antibiotic prophylaxis to ...

New research in JAMA Internal Medicine has challenged the current guideline recommending 5-7 days of preventive antibiotics ...

Prophylactic antibiotic use before tunneled cuffed catheter insertion was not linked to a lower rate of early hemodialysis catheter-related bloodstream infections, a study found.“Tunneled central ...

This raises the possibility that preventive strategies should vary based on the type of mitral surgery, but more research is needed.

Follow-up periods ranged from 2 to 28 days. For overall antibiotic prophylaxis, the relative risk reduction was 64%, the absolute risk reduction was 15%, and the number needed to treat was 8.

The authors evaluated more than 670,000 operations, of which antibiotic prophylaxis was used in 348,119.

The rationale for antibiotic prophylaxis prior to dental work stems from the pathophysiological model that late PJI (occurring at least 3 months after arthroplasty, and often much later) are ...

Perioperative antibiotic prophylaxis that lasts for 24 hours or less is as protective against surgical site infections as extended prophylaxis in patients undergoing cystectomy with ileal urinary ...